Why are toxins not broken down efficiently within the body? It is usually due to poor liver health. The liver, as the second largest organ in our body, is the primary organ that detoxifies toxins in our body. When your liver begins to weaken, toxins are gradually eliminated through your skin. You may start to notice some unobtrusive, minor skin issues such as dull skin tone, pigmentation (always considered as signs of aging); then progressing to dry, red, itchy inflamed skin or yellowish discolouration.